Editorial / Commentary

• Karim, M. E. (2013) Can joint replacement reduce cardiovascular risk? BMJ. 347:f6651

Letter to the Editor / Reply

Refereed Articles

• Karim, M. E.; Pang, M.; Platt, R.W. (2018) Can We Train Machine Learning Methods to outperform the High-dimensional Propensity Score Algorithm? Epidemiology, 29(2): 191-198.
• Related: Presented at an invited session at 2016 IBC conference.

• Karim, M. E.; Petkau, J.; Gustafson, P.; Platt, R.W.; Tremlett, H. and BeAMS study group. (2018) Comparison of Statistical Approaches Dealing with Time-dependent Confounding in Drug Effectiveness Studies. Statistical Methods in Medical Research. 27(6) 1709-1722.
• Related: supporting information

• Karim, M. E.; Platt, R.W. and BeAMS study group. (2017) Estimating inverse probability weights using super learner when weight-model specification is unknown in a marginal structural Cox model context, Statistics in Medicine, 36(13):2032-2047.
• Related: Travel Award from the Statistical Society of Canada Biostatistics Section, 2016 (details)

• Karim, M. E.; Petkau, J.; Gustafson, P.; Tremlett, H. and BeAMS study group. (2016) On the application of statistical learning approaches to construct inverse probability weights in marginal structural Cox models: hedging against weight-model misspecification. Communications in Statistics - Simulation and Computation, 46 (10): 7668-7697.
• Related: Statistics on Reels participation award (CANSSI-sponsored) in the 2015 SSC Student Conference (details, news)

• Karim, M. E.; Gustafson, P.; Petkau, J.; Tremlett, H. and BeAMS study group. (2016) Comparison of Statistical Approaches for Dealing With Immortal Time Bias in Drug Effectiveness Studies. American Journal of Epidemiology, 184 (4): 325-335.
• Related: supporting information
• Related: Student Research Presentations Award in the 2015 annual SSC Meeting  (details, photo)
• Related: Travel Award from the endMS Research and Training Network
• Related: Follow-up: Letter to editor, Reply

• Karim, M. E.; Gustafson, P. (2016) Hypothesis Testing for an Exposure-Disease Association in Case-Control Studies under Non-differential Exposure Misclassification in the presence of Validation Data: Bayesian and Frequentist Adjustments. Statistics in Biosciences. 8 (2): 234–252.
• Related: Presented at an invited session at a conference.

• Karim, M. E.; Gustafson, P.; Petkau, J.; Zhao, Y.; Shirani, A.; Kingwell, E.; Evans, C.; van der Kop, M.; Oger , J.; Tremlett, H. (2014) Marginal structural Cox models for estimating the association between beta-interferon exposure and disease progression in a multiple sclerosis cohort. American Journal of Epidemiology; 180 (2): 160-171.
• Related: supporting information
• Related: Selected as one of the American Journal of Epidemiology (AJE)’s 2014 top 10 Articles of the Year (announcement, open collection, news, certificate)
• Related: Travel Award from the endMS Research and Training Network

• Fontela, P.S.; Quach, C; Karim, M. E.; Willson, D.; Gilfoyle, E.; McNally, J.D.; Gonzales, M.; Papenburg, J.; Reynolds, S.; Lacroix, J.; on behalf of Canadian Critical Care Trials Group and Pediatric Acute Lung Injury and Sepsis Investigators. (2017) Determinants of Antibiotic Tailoring In Pediatric Intensive Care: a National Survey, Pediatric Critical Care Medicine: Published online: June 28, 2017 DOI: 10.1097/PCC.0000000000001238.

• Zhang, T.; Shirani, A.; Zhao, Y.; Karim, M. E.; Gustafson, P.; Petkau, J.; Evans, C.; Kingwell, E.; van der Kop, M.; Zhu, F.; Oger , J.; Tremlett, H. (2015) Beta-interferon exposure and onset of secondary progressive multiple sclerosis, European Journal of Neurology. 22(6):990–1000.

• Shirani A., Zhao, Y. Petkau J., Gustafson P., Karim, M. E., Evans C., Kingwell E., van der Kop M.L., Oger j. and Tremlett H. (2015) Multiple sclerosis in older adults: the clinical profile and impact of interferon beta treatment, BioMed Research International. DOI: 10.1155/2015/451912, 2015 (2015), ID 451912:1-11.

• Gibbs, E.; Karim, M. E.; Oger , J; the Steering Committee of the BENEFIT study (Gilles Edan, Mark S. Freedman, Hans Peter Hartung, Ludwig Kappos, David Miller, Xavier Montalbán, Dirk Pleimes, Christoph Pohl, Chris Polman, Rupert Sandbrink). Antibody dissociation rates are predictive of neutralizing antibody (NAb) course: A comparison of interferon beta-1b-treated patients with transient versus sustained NAbs. Clinical Immunology. 157(1):91–101. 

• Shirani, A.; Zhao, Y.; Karim, M. E.; Petkau, J.; Gustafson, P.; Evans, C.; Kingwell, E.; van der Kop, M.; Oger , J.; Tremlett, H. (2014) Investigation of heterogeneity in the association between interferon beta and disability progression in multiple sclerosis: an observational study. European Journal of Neurology. 21(6):835-44. 

• Shirani, A.; Zhao, Y.; Karim, M. E.; Evans, C.; Kingwell, E.; van der Kop, M.; Oger , J.; Gustafson, P.; Petkau, J.; Tremlett, H. (2012). Association between use of interferon beta and progression of disability in patients with relapsing-remitting multiple sclerosis. Journal of the American Medical Association (JAMA). 308(3):247-256. 
• Related: Journal Media Release (JAMA media link, 46 papers selected each year)
• Related: Video Interview and Additional Video Comments. 
• Related: Selected for an Accompanying Editorial (Editorial Link).
• Related: Extensive Media Attention: 4 T.V. interviews (live on CTV National, taped on multiple evening news networks), and extensive news coverage, including NY Times, Fox News, Time, CBC News, Metro News,  Global BC, Vancouver Sun, MS Society of Canada, UBC media, UBC Stat Dept News.
• Related: Follow-up: Letter to editor, Reply, Commentary, Citations.
• Related: Officially recognized in the ‘2013 International Year of Statistics – Recognizing the Contributions of Statistics to Society worldwide’ poster.

• Rahman, P.K.; Matsui, N.; Ikemoto, Y.; Karim, M. E. (2007). Intergenerational Mobility in Poverty State of Chronically Poor in Rural Bangladesh: A Markov Chain Model Approach. Asian Economic Review, Yamaguchi University, Vol-66, No.1, 2007 (mirror)